Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 3.9K citations · Full text

Cell Autophagy, Mitophagy, Mitochondrial Function +11

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.8K citations · Full text

Pink1 Accumulation, Mitophagy, Activate Parkin +18

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

Seok Min Jin, Michael Lazarou, Chunxin Wang et al. · The Journal of Cell Biology · 2010 · 1.3K citations · Full text

Two nuclear mutations that block mitochondrial protein import in yeast.

Michael P. Yaffe, Gottfried Schatz · Proceedings of the National Academy of Sciences · 1984 · 519 citations · Full text

Mitochondrial Function, Genetics, Mitochondrial Structure +9

PINK1 cleavage at position A103 by the mitochondrial protease PARL

Emma Deas, Hélène Plun‐Favreau, Sonia Gandhi et al. · Human Molecular Genetics · 2010 · 478 citations · Full text

Mitochondrial Dynamic, Neurodegenerative Diseases, Mitochondrial Function +15