Modulation of Cholesterol Homeostasis by Antiproliferative Drugs in Human Pterygium Fibroblasts

Abstract

Intracellular modifications of cholesterol homeostasis may be relevant to pterygium development. Moreover, antiproliferative agents such as PIO and EVE may represent a potential topical medication in the prevention and inhibition of pterygium growth at an early stage, probably by modulation of cholesterol ester metabolism.