Concepedia

A Reduction in Pten Tumor Suppressor Activity Promotes ErbB-2-Induced Mouse Prostate Adenocarcinoma Formation through the Activation of Signaling Cascades Downstream of PDK1

Olga Rodriguez, Edwin W. Lai, Sarada Vissapragada, Caroline Cromelin, Maral Avetian, Patricia C. Salinas, Hida Ramos, Bhaskar Kallakury, Mathew C. Casimiro, Michael P. Lisanti,

American Journal Of Pathology · 2009 · 19 citations · 33 references

DOIFull text

Open access

Concepts

References

33

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Zhenbang Chen, Lloyd C. Trotman, David R. Shaffer et al. · Nature · 2005 · 2K citations · Full text

, , +16

Pten is essential for embryonic development and tumour suppression

Antonio Di Cristofano, Bárbara Pesce, Carlos Cordon‐Cardo et al. · Nature Genetics · 1998 · 1.5K citations

, , +14

mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

Diane C. Fingar, Celeste Richardson, Andrew R. Tee et al. · Molecular and Cellular Biology · 2003 · 873 citations · Full text

, , +17

Transforming p21 Mutants and c-Ets-2 Activate the Cyclin D1 Promoter through Distinguishable Regions

Chris Albanese, Janet Johnson, Genichi Watanabe et al. · Journal of Biological Chemistry · 1995 · 806 citations · Full text

, , +13

Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis

Shidong Jia, Zhenning Liu, Sen Zhang et al. · Nature · 2008 · 684 citations · Full text

, , +16