Hepatoprotective activity of Boerhaavia diffusa Linn. against country made liquor induced hepatotoxicity in albino rats fed on controlled calorie diet

Abstract

1. The effect of 50% ethanolic extract of roots of Boerhaavia diffusa on country made liquor (C. M. L.) induced hepatotoxicity was studied in albino rats. 2. B. diffusa (100 mg/100 g body weight/day) protected the rats from hepatotoxic action of C. M. L. as evidenced by changes in serum alanine aminotransferase (ALT), Triglycerides (TG), Cholesterol and total lipid levels in both serum and tissues. 3. Histopathological studies showed marked reduction in fat deposits in animals receiving B. diffusa along with C. M. L.