Concepedia

Potential antifolate resistance determinants and genotypic variation in the bifunctional dihydrofolate reductase-thymidylate synthase gene from human and bovine isolates of Cryptosporidium parvum

John R. Vásquez, Lisa Goozé, Kami Kim, Jiří Gut, Carolyn Petersen, Richard G. Nelson

Molecular and Biochemical Parasitology · 1996 · 101 citations · 34 references

DOI

Concepts

References

34

Principles and Practice of Infectious Diseases.

Annals of Internal Medicine · 1991 · 12.1K citations

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Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

Gilbert Chu, Douglas Vollrath, Ronald W. Davis · Science · 1986 · 1.5K citations

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Prosite: a dictionary of sites and patterns in proteins

Amos Bairoch · Nucleic Acids Research · 1992 · 933 citations · Full text

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Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

J.T. Bolin, David J. Filman, David A. Matthews et al. · Journal of Biological Chemistry · 1982 · 745 citations · Full text

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Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

David S. Peterson, David Walliker, Thomas E. Wellems · Proceedings of the National Academy of Sciences · 1988 · 657 citations · Full text

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