Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

M.D. Burke, S. Thompson, Clifford R. Elcombe et al. · Biochemical Pharmacology · 1985 · 1.3K citations

Medicine, Pharmacology, Drug Metabolism +8

CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes

Gang Luo, Mark R. Cunningham, Sean Kim et al. · Drug Metabolism and Disposition · 2002 · 447 citations

Medicine, Pharmacology, Biochemical Pharmacology +15

Dual effect of dexamethasone on <i>CYP3A4</i> gene expression in human hepatocytes

Jean‐Marc Pascussi, Lionel Drocourt, Sabine Gerbal‐Chaloin et al. · European Journal of Biochemistry · 2001 · 299 citations · Full text

Medicine, Biochemistry, Pharmacology +12

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene

Klaus Gellner, Regina Eiselt, Elisabeth Hustert et al. · Pharmacogenetics · 2001 · 226 citations

Medicine, Genetics, Pharmacology +15

Drug metabolism in hepatocyte sandwich cultures of rats and humans

A. D. Kern, A. Bader, R. Pichlmayr et al. · Biochemical Pharmacology · 1997 · 187 citations

Medicine, Biochemistry, Pharmacology +12