Concepedia

Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A

Woen Ping Siu, Pamela Boon Li Pun, Calivarathan Latchoumycandane, Urs A. Boelsterli

Toxicology and Applied Pharmacology · 2008 · 57 citations · 38 references

DOI

Concepts

References

38

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

Xu Luo, I. Imawati Budihardjo, Hua Zou et al. · Cell · 1998 · 3.6K citations · Full text

, , +16

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

, , +17

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature · 1999 · 2.2K citations

, , +10

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

Michael C. Wei, Tullia Lindsten, Vamsi K. Mootha et al. · Genes & Development · 2000 · 1.3K citations · Full text

, , +17

Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial Membrane

Robert Eskes, Solange Desagher, Bruno Antonsson et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

, , +9