Concepedia

Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR

Claudia Luckert, Anke Ehlers, Thorsten Buhrke, Albrecht Seidel, Alfonso Lampen, Stefanie Hessel‐Pras

Toxicology Letters · 2013 · 90 citations · 28 references

DOI

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References

28

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

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Measurement of protein using bicinchoninic acid

Pam Smith, Randall I. Krohn, Greg T. Hermanson et al. · Analytical Biochemistry · 1985 · 18.4K citations

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1997 · 2.2K citations · Full text

, , +16

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene

Tatsuya Sueyoshi, Takeshi Kawamoto, Igor N. Zelko et al. · Journal of Biological Chemistry · 1999 · 671 citations · Full text

, , +17