The creation of diversity in the human immunoglobulin Vλ repertoire

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

Anthony Nicholls, Kim A. Sharp, Barry Honig · Proteins Structure Function and Bioinformatics · 1991 · 5.2K citations

Natural Sciences, Biochemistry, Biophysics +17

A simple and very efficient method for generating cDNA libraries

Ueli Gubler, Beth J. Hoffman · Gene · 1983 · 4.6K citations

Life Sciences, Molecular Biology, Molecular Genetics +10

Somatic generation of antibody diversity

Susumu Tonegawa · Nature · 1983 · 4K citations

Life Sciences, Biotechnology, Immunology +14

Somatic generation of antibody diversity.

PubMed · 1976 · 3.3K citations

Life Sciences, Biotechnology, Immunology +14