<i>Candida</i> spp. with Acquired Echinocandin Resistance, France, 2004–20101

Éric Dannaoui, Marie Desnos‐Ollivier, Dea Garcia‐Hermoso, Frédéric Grenouillet, Sophie Cassaing, Marie-Thérèse Baixench, Stéphane Bretagne, Françoise Dromer, Olivier Lortholary

Emerging infectious diseases · 2012 · 126 citations · 12 references

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Abstract

We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.

References

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