Guillermo García‐Effrón

A New <i>Aspergillus fumigatus</i> Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of <i>cyp51A</i> Alterations

Emilia Mellado, Guillermo García‐Effrón, Laura Alcázar‐Fuoli et al. · Antimicrobial Agents and Chemotherapy · 2007 · 489 citations · Full text

Effect of <i>Candida glabrata FKS1</i> and <i>FKS2</i> Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β- <scp>d</scp> -Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

Guillermo García‐Effrón, Samuel Lee, Steven Park et al. · Antimicrobial Agents and Chemotherapy · 2009 · 310 citations · Full text

Biosynthesis, Engineering, Cellular Enzymology +14

A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in <i>Candida parapsilosis</i> , <i>Candida orthopsilosis</i> , and <i>Candida metapsilosis</i> Accounts for Reduced Echinocandin Susceptibility

Guillermo García‐Effrón, Säntosh K. Katiyar, Steven Park et al. · Antimicrobial Agents and Chemotherapy · 2008 · 306 citations · Full text

Reduced Echinocandin Susceptibility, Medical Microbiology, Antifungal Agent +15

Correlating Echinocandin MIC and Kinetic Inhibition of <i>fks1</i> Mutant Glucan Synthases for <i>Candida albicans</i> : Implications for Interpretive Breakpoints

Guillermo García‐Effrón, Steven Park, David S. Perlin · Antimicrobial Agents and Chemotherapy · 2008 · 250 citations · Full text

Antifungal Agent, Hot Spot 1, Susceptibility Breakpoint +14

Substitutions at Methionine 220 in the 14α-Sterol Demethylase (Cyp51A) of <i>Aspergillus fumigatus</i> Are Responsible for Resistance In Vitro to Azole Antifungal Drugs

Emilia Mellado, Guillermo García‐Effrón, Laura Alcázar‐Fuoli et al. · Antimicrobial Agents and Chemotherapy · 2004 · 204 citations · Full text

Aspergillus Fumigatus, Fungal Cell Biology, Genetics +18