Guillermo García‐Effrón

A New <i>Aspergillus fumigatus</i> Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of <i>cyp51A</i> Alterations

Emilia Mellado, Guillermo García‐Effrón, Laura Alcázar‐Fuoli et al. · Antimicrobial Agents and Chemotherapy · 2007 · 498 citations · Full text

Life Sciences, Genetics, Microbiology +16

A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in <i>Candida parapsilosis</i> , <i>Candida orthopsilosis</i> , and <i>Candida metapsilosis</i> Accounts for Reduced Echinocandin Susceptibility

Guillermo García‐Effrón, Säntosh K. Katiyar, Steven Park et al. · Antimicrobial Agents and Chemotherapy · 2008 · 316 citations

Life Sciences, Infectious Diseases, Microbiology +17

Effect of <i>Candida glabrata FKS1</i> and <i>FKS2</i> Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β- <scp>d</scp> -Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

Guillermo García‐Effrón, Samuel Lee, Steven Park et al. · Antimicrobial Agents and Chemotherapy · 2009 · 316 citations · Full text

Life Sciences, Genetics, Microbiology +17

Correlating Echinocandin MIC and Kinetic Inhibition of <i>fks1</i> Mutant Glucan Synthases for <i>Candida albicans</i> : Implications for Interpretive Breakpoints

Guillermo García‐Effrón, Steven Park, David S. Perlin · Antimicrobial Agents and Chemotherapy · 2008 · 255 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Substitutions at Methionine 220 in the 14α-Sterol Demethylase (Cyp51A) of <i>Aspergillus fumigatus</i> Are Responsible for Resistance In Vitro to Azole Antifungal Drugs

Emilia Mellado, Guillermo García‐Effrón, Laura Alcázar‐Fuoli et al. · Antimicrobial Agents and Chemotherapy · 2004 · 207 citations · Full text

Life Sciences, Microbiology, Molecular Genetics +17