Everolimus and mycophenolate mofetil are potent inhibitors of fibroblast proliferation after lung transplantation1

Abstract

RAD and MMF were the most potent antifibroproliferative drugs and were effective at concentrations achieved clinically, supporting their use for the treatment of patients with early BO. Our method holds promise as an in vitro model to assess the likely in vivo responses of human lung fibroblasts to specific immunosuppressive drugs.