Structural features of a snake venom thrombin-like enzyme: thrombin and trypsin on a single catalytic platform?

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

The refined 1.9‐Å X‐ray crystal structure of d‐Phe‐Pro‐Arg chloromethylketone‐inhibited human <i>α</i>‐thrombin: Structure analysis, overall structure, electrostatic properties, detailed active‐site geometry, and structure‐function relationships

Wolfram Bode, Andrej Karshikov · Protein Science · 1992 · 626 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The geometry of the reactive site and of the peptide groups in trypsin, trypsinogen and its complexes with inhibitors

Markus Marquart, J. Walter, J. Deisenhofer et al. · Acta Crystallographica Section B Structural Science · 1983 · 583 citations

Life Sciences, Biochemistry, Molecular Biology +13

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

Alfred Rühlmann, D. Kukla, P. Schwager et al. · Journal of Molecular Biology · 1973 · 448 citations

Life Sciences, Biochemistry, Molecular Biology +10

Homology modeling, model and software evaluation: three related resources.

Rolando Rodríguez, Glay Chinea, Nicolás López et al. · Bioinformatics · 1998 · 344 citations · Full text

Life Sciences, Bioinformatics, Computational Biology +7