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Aspermia and Recovery of Spermatogenesis in Cancer Patients Following Incidental Gonadal Irradiation during Treatment: A Progress Report
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1976
Year
SpermatogenesisFertilityReproductive HealthSemen AnalysisCancer PatientsReproductive BiologyBrachytherapyGametogenesisPublic HealthRadiation OncologyGonadal DoseInfertilityAndrologyProgress ReportClinical TherapyHormonal Male ContraceptionHuman ReproductionUrologyIncidental Gonadal IrradiationMedicine
The 11 patients in this study who received incidental gonadal irradiation from clinical therapy all became aspermic within 8-34 weeks following treatment. The estimated gonadal dose was 118-228 rads. Five of these patients have shown recovery of spermatogenesis; 3 of these have reached fertilizable concentrations. Recovery of semen sperm was noted at 44-77 weeks following treatment. The other 2 patients, after 110-176 weeks, have sub-fertile concentrations of semen sperm. Five patients have not been followed for a sufficient length of time to permit recovery to be noted.