MDR1 P-gp Expression and Activity in Intact Human Placental Tissue; Upregulation by Retroviral Transduction

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

Medicine, Cell Biology, Pharmacology +11

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

Ira Pastan, Michael M. Gottesman, Kazumitsu Ueda et al. · Proceedings of the National Academy of Sciences · 1988 · 491 citations · Full text

Life Sciences, Microbiology, Pharmacology +11

MATERNAL EPILEPSY AND ABNORMALITIES OF THE FETUS AND NEWBORN

B D Speidel, S R Meadow · The Lancet · 1972 · 420 citations

Medicine, Obstetrics, Pediatrics +14

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation.

James R. Bartles, H. Feracci, Bruno Stieger et al. · The Journal of Cell Biology · 1987 · 382 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

Johan W. Smit, Maarten T. Huisman, Olaf van Tellingen et al. · Journal of Clinical Investigation · 1999 · 355 citations · Full text

Pharmacy, Pharmacology, Toxicology +17