Concepedia

The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection

Laurieann Casey Klockow, Hamayun J. Sharifi, Xiaoyun Wen, Andrea Furuya, Michael Nekorchuk, Carlos M. C. de Noronha

Virology · 2013 · 55 citations · 89 references

DOI

Concepts

References

89

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

Thimmaiah P. Chendrimada, Richard I. Gregory, Easwari Kumaraswamy et al. · Nature · 2005 · 2.1K citations · Full text

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli et al. · Nature · 2011 · 1.5K citations

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Vpr Is Required for Efficient Replication of Human Immunodeficiency Virus Type-1 in Mononuclear Phagocytes

Ruth I. Connor, Benjamin K. Chen, Sunny Choe et al. · Virology · 1995 · 1.3K citations · Full text

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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Kasia Hrecka, Caili Hao, Magda Gierszewska et al. · Nature · 2011 · 1.2K citations

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Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

Xianghui Yu, Yunkai Yu, Bindong Liu et al. · Science · 2003 · 1.2K citations

, , +13