Enhancement of the in vivo circulation lifetime of l-α-distearoylphosphatidylcholine liposomes: importance of liposomal aggregation versus complement opsonization

Microdetermination of Phosphorus

P. S. Chen, T. Y. Toribara, Huber R. Warner · Analytical Chemistry · 1956 · 7.2K citations

Natural Sciences, Chemistry, Analytical Chemistry +8

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Alexander L. Klibanov, Kazuo Maruyama, Vladimir P. Torchilin et al. · FEBS Letters · 1990 · 2K citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Vesicles of variable sizes produced by a rapid extrusion procedure

L.D. Mayer, Michael J. Hope, Pieter R. Cullis · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1986 · 1.7K citations

Engineering, Materials Engineering, Membrane Trafficking +8

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

Demetrios Papahadjopoulos, Theresa M. Allen, Alberto Gabizón et al. · Proceedings of the National Academy of Sciences · 1991 · 1.6K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

Theresa M. Allen, Cecilie Cetti Hansen, Francisco J. Plaza Martín et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 1.4K citations

Pharmacy, Pharmacokinetics, Pharmacology +15