Mouse liver glutathione S-transferase mediated metabolism of methylene chloride to a mutagen in the CHO/HPRT assay

Theta, a new class of glutathione transferases purified from rat and man

David J. Meyer, B Coles, Sally Pemble et al. · Biochemical Journal · 1991 · 737 citations · Full text

Life Sciences, Biochemistry, Biocatalysis +11

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride

Melvin E. Andersen, Harvey J. Clewell, Michael L. Gargas et al. · Toxicology and Applied Pharmacology · 1987 · 634 citations

Pharmacy, Pharmacokinetics, Toxicology +10

A simple, sensitive assay to detect DNA–protein cromlinks in intact cells and <i>in vivo</i>

Anatoly Zhitkovich, Max Costa · Carcinogenesis · 1992 · 248 citations

Life Sciences, Biochemistry, Molecular Biology +14

Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes.

Ricarda Thier, J B Taylor, Sally Pemble et al. · Proceedings of the National Academy of Sciences · 1993 · 189 citations · Full text

Pharmacy, Molecular Biology, Toxicology +17

In vitro metabolism of methylene chloride in human and animal tissues: Use in physiologically based pharmacokinetic models

Richard H. Reitz, Alan L. Mendrala, F. Peter Guengerich · Toxicology and Applied Pharmacology · 1989 · 138 citations

Pharmacy, Pharmacokinetics, Pharmacology +9