Concepedia

Base-induced side reactions in Fmoc-solid phase peptide synthesis: Minimization by use of piperazine as Nα-deprotection reagent

John D. Wade, Marc Mathieu, Mary Macris, Geoffrey W. Tregear

International Journal of Peptide Research and Therapeutics · 2000 · 50 citations · 16 references

DOI

Concepts

References

16

The 9-fluorenylmethyloxycarbonyl family of base-sensitive amino-protecting groups

Louis A. Carpino · Accounts of Chemical Research · 1987 · 184 citations

, , +10

Sequence dependence of aspartimide formation during 9-fluorenylmethoxycarbonyl solid-phase peptide synthesis

Janelle Lauer, Cynthia G. Fields, Gregg B. Fields · Letters in Peptide Science · 1995 · 153 citations

, , +6

Diketopiperazine formation in solid phase peptide synthesis using p-alkoxybenzyl ester resins and Fmoc-amino acids

Enrique Pedroso, Anna Grandas, F. Xavier de las Heras et al. · Tetrahedron Letters · 1986 · 137 citations

, , +10

Formation of aspartimide peptides in Asp-Gly sequences

Ernesto Nicolás, Enrique Pedroso, Ernest Girald · Tetrahedron Letters · 1989 · 117 citations

, , +5

Removal of 9-fluorenylmethyloxycarbonyl (Fmoc) group with tetrabutylammonium fluoride

Masaaki Ueki, Masahide Amemiya · Tetrahedron Letters · 1987 · 106 citations

, , +3