Stroke · 1994 · 41 citations · 6 references
MedicineNeurologyNeuroscienceCerebrovascular NeurosurgeryNeurocritical CarePoisoning ManagementAcute Ischemic StrokeCerebrovascular DiseaseCerebrovascular ImagingHypoxic-ischemic Brain InjuryNeurovascular DysfunctionStrokeCerebral InjuryCerebral Vascular TerritoriesFocal Neurological DeficitsFrontal Release SignsHyperbaric ExposureHyperbaric InterventionNeuroimaging DiagnosticsStroke Neuroimaging
BACKGROUND: We report the clinical and neuroimaging findings of a patient who sustained multiple cerebral infarcts after the ingestion of concentrated hydrogen peroxide solution sold as a "health food" product. CASE DESCRIPTION: An 84-year-old man sustained focal neurological deficits immediately after ingesting 30 mL of 35% hydrogen peroxide solution. Physical examination disclosed a left hemiparesis, frontal release signs, and cerebellar dysfunctions. Magnetic resonance imaging revealed multiple cerebral and cerebellar infarctions in the anterior, middle, and posterior vascular territories. CONCLUSIONS: The likely mechanism of pathogenesis involves cerebral oxygen gas embolization. The use of hyperbaric therapy should be considered in treating hydrogen peroxide poisoning.
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Red Cell Metabolism: A Manual of Biochemical Methods.
Annals of Internal Medicine · 1971 · 2.3K citations
Fatal oxygen embolization after hydrogen peroxide ingestion
DAVID W. CHRISTENSEN, William E. Faught, Richard E. Black et al. · Critical Care Medicine · 1992 · 54 citations
Gas Embolism After Ingestion of Hydrogen Peroxide
Wayne Rackoff, DAVID F. MERTON · PEDIATRICS · 1990 · 48 citations