Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis

The 1982 revised criteria for the classification of systemic lupus erythematosus

Eng M. Tan, Alan S. Cohen, James F. Fries et al. · Arthritis & Rheumatism · 1982 · 14.6K citations

Life Sciences, Immunology, Internal Medicine +14

IMMUNOLOGY OF DNA. III. <i>CRITHIDIA LUCILIAE</i>, A SIMPLE SUBSTRATE FOR THE DETERMINATION OF ANTI‐dsDNA WITH THE IMMUNOFLUORESCENCE TECHNIQUE*

L. A. Aarden, Els R. de Groot, T. E. W. Feltkamp · Annals of the New York Academy of Sciences · 1975 · 565 citations

Life Sciences, Immunology, Molecular Biology +16

In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus.

Shozo Izui, P H Lambert, P. A. Miescher · The Journal of Experimental Medicine · 1976 · 314 citations · Full text

Life Sciences, Biochemistry, Immunology +9

Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney.

Eyal Raz, Mayer Brezis, E. Rosenmann et al. · The Journal of Immunology · 1989 · 276 citations · Full text

Medicine, Immunology, Nephrology +17

Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo.

Cornelis Kramers, Machteld N. Hylkema, Marie‐Charlotte Brüggen et al. · Journal of Clinical Investigation · 1994 · 267 citations · Full text

Life Sciences, Immunology, Molecular Biology +13