Selective Domino Ring-Closing Metathesis−Cross-Metathesis Reactions between Enynes and Electron-Deficient Alkenes

Abstract

[reaction: see text] A selective domino ring-closing metathesis (RCM)-cross-metathesis (CM) process between enynes and electron-deficient alkenes is reported. The conditions have been optimized for enynes 3 and methyl acrylate with catalyst IV. The scope and limitations of this reaction are described, and a possible mechanism is discussed.