Reduction of G Protein-Coupled Receptor Kinase 2 Expression in U-937 Cells Attenuates H2 Histamine Receptor Desensitization and Induces Cell Maturation

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Desensitization of G-protein-coupled Receptors

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Life Sciences, Biochemistry, Molecular Biology +17

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.

Martin J. Lohse, J.L. Benovic, M G Caron et al. · Journal of Biological Chemistry · 1990 · 398 citations · Full text

Medicine, Pharmacology, Cell Signaling +14

Cloning, Expression, and Pharmacological Characterization of a Novel Human Histamine Receptor

Yuan Zhu, David Michalovich, Hsiao-Ling Wu et al. · Molecular Pharmacology · 2001 · 313 citations · Full text

Medicine, Pharmacology, Cell Signaling +13

The Small GTP-binding Protein Rho Activates c-Jun N-terminal Kinases/Stress-activated Protein Kinases in Human Kidney 293T Cells

Hidemi Teramoto, Piero Crespo, Omar A. Coso et al. · Journal of Biological Chemistry · 1996 · 174 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14