Concepedia

Desensitization Studies

Desensitization Studies is a systematic research framework in cell signaling biophysics that characterizes the molecular mechanisms and kinetic dynamics by which G protein-coupled receptors, hormone signal transduction pathways, and ion channel signaling systems attenuate their responsiveness to persistent or repeated stimuli.

325

Publications

15.9K

Citations

1.3K

Authors

415

Institutions

Publications per year

2017–2026

20

Parents

Publications

325

A randomized controlled study of peanut oral immunotherapy: Clinical desensitization and modulation of the allergic response

Pooja Varshney, Stacie M. Jones, Amy M. Scurlock et al. · Journal of Allergy and Clinical Immunology · 2011 · 560 citations · Full text

, , +16

Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by con A

James E. Huettner · Neuron · 1990 · 421 citations

, , +16

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart.

Martin Ungerer, Giustino Parruti, Michael Böhm et al. · Circulation Research · 1994 · 297 citations

, , +12

HIV-1 Tat protein mimicry of chemokines

Adriana Albini, Silvano Ferrini, Roberto Benelli et al. · Proceedings of the National Academy of Sciences · 1998 · 277 citations

, , +17

Direct observation of substance P-induced internalization of neurokinin 1 (NK1) receptors at sites of inflammation.

Jeffrey J. Bowden, Adella Garland, P.A. Lefevre et al. · Proceedings of the National Academy of Sciences · 1994 · 255 citations

, , +15

1–5 of 325

Authors

1.3K

  1. NA
    Norio Akaike

    Kyushu University, Japan

    4 publications · 184 citations

    4

    h-index

  2. JW
    Julia Winkler

    New Frontier, United States

    3 publications · 72 citations

    3

    h-index

  3. ES
    Ekaterini Syrigou

    Sotiria General Hospital, Greece

    3 publications · 117 citations

    3

    h-index

  4. AM
    Arthur M. Silverstein

    Johns Hopkins University, United States

    3 publications · 145 citations

    3

    h-index

  5. ST
    Stanley T. Crooke

    Ionis Pharmaceuticals (United States), United States

    3 publications · 72 citations

    3

    h-index

1–5 of 1.3K

Institutions

415

  1. Duke Medical Center

    Durham, United States

    12 h-index

    44 publications

    8.8K citations

  2. Duke University Hospital

    Durham, United States

    12 h-index

    33 publications

    4.2K citations

  3. National Institutes of Health

    Bethesda, United States

    7 h-index

    23 publications

    985 citations

  4. Harvard University

    Cambridge, United States

    7 h-index

    22 publications

    1.4K citations

  5. University of Toronto

    Toronto, Canada

    6 h-index

    11 publications

    609 citations

  6. Massachusetts General Hospital

    Boston, United States

    6 h-index

    14 publications

    1.1K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    19 publications

    2.4K citations

  8. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    18 publications

    456 citations

1–8 of 415

Venues

  1. Journal of Biological Chemistry

    JBC · 29 publications · 2K citations

    25

    h-index

  2. British Journal of Pharmacology

    BJP · 15 publications · 527 citations

    15

    h-index

  3. PubMed

    Repository · 20 publications · 494 citations

    15

    h-index

  4. 12

    h-index

  5. Molecular Pharmacology

    10 publications · 793 citations

    10

    h-index

1–5