Concepedia

Increasing Adiposity Is Associated With Higher Adipokine Levels and Lower Bone Mineral Density in Obese Older Adults

Lina Aguirre, Nicola Napoli, Debra L. Waters, Clifford Qualls, Dennis T. Villareal, Reina Armamento‐Villareal

The Journal of Clinical Endocrinology & Metabolism · 2014 · 86 citations · 37 references

DOIFull text

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Abstract

Increasing adiposity together with decreasing lean mass is associated with lower BMD, higher adipokine levels, and worsening frailty in elderly obese adults.

References

37

Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

Christian Weyer, Tohru Funahashi, Sachiyo Tanaka et al. · The Journal of Clinical Endocrinology & Metabolism · 2001 · 3.4K citations · Full text

Leptin Inhibits Bone Formation through a Hypothalamic Relay

Patricia Ducy, Michael Amling, Shu Takeda et al. · Cell · 2000 · 2.1K citations · Full text

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Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

I. Sadaf Farooqi, Susan A. Jebb, Gill Langmack et al. · New England Journal of Medicine · 1999 · 2K citations · Full text

, , +25

Leptin Regulates Bone Formation via the Sympathetic Nervous System

Shu Takeda, Florent Elefteriou, Régis Levasseur et al. · Cell · 2002 · 1.7K citations · Full text

, , +8

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

I. Sadaf Farooqi, Giuseppe Matarese, Graham M. Lord et al. · Journal of Clinical Investigation · 2002 · 1.3K citations · Full text