Synergistic dual-targeting hydrogel improves targeting and anticancer effect of Taxol in vitro and in vivo

Chang Shu, Ruixin Li, Yajun Yin, Deyan Yin, Yueqing Gu, Ding Li, Wenying Zhong

Chemical Communications · 2014 · 35 citations · 26 references

Concepts

Abstract

A synergistic dual-targeting molecular self-assembly hydrogel was designed with estrone (Et) and Arg-Gly-Asp (RGD) peptide. Confocal imaging in vitro and real-time visualization in vivo researches were carried out to evidence enhanced targeted delivery and anticancer effect of Taxol.

References

26