Genetic susceptibility to pregnancy-related venous thromboembolism: Roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations

Mutation in blood coagulation factor V associated with resistance to activated protein C

Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al. · Nature · 1994 · 3.8K citations

Medicine, Genetics, Hematology +14

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

SR Poort, FR Rosendaal, PH Reitsma et al. · Blood · 1996 · 3.1K citations · Full text

Medicine, Genetics, Molecular Genetics +15

Resistance to Activated Protein C as a Basis for Venous Thrombosis

Peter J. Svensson, Björn Dahlbäck · New England Journal of Medicine · 1994 · 1.1K citations · Full text

Medicine, Hematology, Clinical Biochemistry +13

Hyperhomocysteinemia as a Risk Factor for Deep-Vein Thrombosis

Martin den Heijer, Ted Koster, Henk J. Blom et al. · New England Journal of Medicine · 1996 · 1.1K citations · Full text

Medicine, Hematology, Clinical Biochemistry +11

Increased fetal loss in women with heritable thrombophilia

F E Preston, FR Rosendaal, I.D. Walker et al. · The Lancet · 1996 · 677 citations

Medicine, Genetics, Obstetrics +12