Multi-site analytical evaluation of a chemiluminescent magnetic microparticle immunoassay (CMIA) for sirolimus on the Abbott ARCHITECT analyzer

Characterization of the FKBP·Rapamycin·FRB Ternary Complex

Laura A. Banaszynski, Corey W. Liu, Thomas J. Wandless · Journal of the American Chemical Society · 2005 · 632 citations

Life Sciences, Molecular Biology, Pharmacology +17

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.

Martin Sattler, F. Peter Guengerich, Chul‐Ho Yun et al. · Drug Metabolism and Disposition · 1992 · 389 citations

Medicine, Biochemistry, Pharmacology +17

Complete Avoidance of Calcineurin Inhibitors in Renal Transplantation: A Randomized Trial Comparing Sirolimus and Tacrolimus

Timothy S. Larson, Patrick G. Dean, Mark D. Stegall et al. · American Journal of Transplantation · 2006 · 299 citations · Full text

Medicine, Nephrology, Pharmacotherapy +16

De Novo Kidney Transplantation Without Use of Calcineurin Inhibitors Preserves Renal Structure and Function at Two Years

Stuart M. Flechner, Sunil M. Kurian, Kim Solez et al. · American Journal of Transplantation · 2004 · 282 citations · Full text

Medicine, Nephrology, Pharmacotherapy +17

Routine clinical monitoring of sirolimus (rapamycin) whole-blood concentrations by HPLC with ultraviolet detection

Kimberly L. Napoli, B D Kahan · Clinical Chemistry · 1996 · 87 citations · Full text

Pharmacy, Pharmaceutical Analysis, Pharmacology +15