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Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer

Radiation OncologyGenome InstabilityGenomic ImbalancesBreast OncologyTumor HeterogeneityMammary TumorsCancer GenomicsBreast CancerCancer GeneticsSystems BiologyMedicineCell BiologyTumor BiologyCentrosome AmplificationHealth Sciences