miR‐181a mediates <scp>TGF</scp>‐β‐induced hepatocyte <scp>EMT</scp> and is dysregulated in cirrhosis and hepatocellular cancer

Abstract

MiR-181a had a direct effect in inducing hepatocyte EMT and was able to replace TGF-β-induced effects in vitro. MiR-181a was over-expressed in cirrhosis and HCC and is likely to play a role in disease pathogenesis.