New Pentacyclic Triterpenes from <i>Gypsophila oldhamiana</i> and Their Biological Evaluation as Glycogen Phosphorylase Inhibitors

Abstract

The three new pentacyclic triterpenes 1-3 were isolated and elucidated from the roots of Gypsophila oldhamiana, together with seven known triterpenes (4-10). These triterpenes were evaluated for their glycogen phosphorylase inhibitory activity and preliminary structure-activity trends are suggested.