Naturally Occurring Pentacyclic Triterpenes as Inhibitors of Glycogen Phosphorylase: Synthesis, Structure−Activity Relationships, and X-ray Crystallographic Studies

Xiaoan Wen, Hongbin Sun, Jun Liu, +12

Journal of Medicinal Chemistry

GlycobiologyGpb-maslinic Acid ComplexesPharmaceutical ChemistryPentacyclic TriterpenesMedicinal Chemistry +16

Efficient propylphosphonic anhydride (®T3P) mediated synthesis of benzothiazoles, benzoxazoles and benzimidazoles

Xiaoan Wen, Jamal El Bakali, Rebecca Deprez‐Poulain, +1

Tetrahedron Letters

Natural SciencesDiversity-oriented SynthesisOrganic ChemistryChemistrySynthesis Method +3

Pentacyclic triterpenes. Part 1: The first examples of naturally occurring pentacyclic triterpenes as a new class of inhibitors of glycogen phosphorylases

Xiaoan Wen, Hongbin Sun, Jun Liu, +4

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryGlycogen PhosphorylasesMedicineNatural Sciences +6

Pentacyclic triterpenes. Part 2: Synthesis and biological evaluation of maslinic acid derivatives as glycogen phosphorylase inhibitors

Xiaoan Wen, Pu Zhang, Jun Liu, +3

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryGlycosylationBiochemistryMedicineNatural Sciences +7

The STING antagonist H‐151 ameliorates psoriasis via suppression of STING/NF‐κB‐mediated inflammation

Yanhong Pan, Yanping You, Li Sun, +8

British Journal of Pharmacology

Electrochemically enabled chemoselective sulfonylation and hydrazination of indoles

Yuzhen Zhang, Zu‐Yu Mo, Heng‐Shan Wang, +3

Green Chemistry

Chemical EngineeringC3-unsubstituted IndolesChemoselective SulfonylationEngineeringOrganic Electrochemistry +8

N-Substituted 3(10<i>H</i>)-Acridones as Visible-Light, Water-Soluble Photocatalysts: Aerobic Oxidative Hydroxylation of Arylboronic Acids

Hongyan Xie, Lishuai Han, Shan Huang, +6

The Journal of Organic Chemistry

Arylboronic AcidsRoom TemperatureChemical EngineeringEngineeringPhotoredox Process +11

Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors

Chao Chen, Jie-Mei Song, Jinzheng Wang, +5

Bioorganic & Medicinal Chemistry Letters

Pharmaceutical ChemistryBiochemistryThiazole DerivativesMedicineRational Drug Design +6

C–H Bond Functionalization via [1,5]-Hydride Shift/Cyclization Sequence: Approach to Spiroindolenines

Pengfei Wang, Chunhuan Jiang, Xiaoan Wen, +2

The Journal of Organic Chemistry

C–h Bond FunctionalizationEngineeringBiochemistryNatural SciencesMajor Isomers +11

Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors

Enqin Li, Wei Zhao, Chenxi Zhang, +5

European Journal of Pharmaceutical Sciences

Medicinal ChemistryMedicineAnti-cancer ActivityAcetyl-coa Carboxylase 1Anti-cancer Agent +6