A potassium channel-linked mechanism of glial cell swelling in the postischemic retina

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

Geoffrey T. Manley, Miki Fujimura, Tonghui Ma et al. · Nature Medicine · 2000 · 1.5K citations

Medicine, Neurology, Neuroscience +17

Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

Søren Nielsen, Erlend A. Nagelhus, Mahmood Amiry‐Moghaddam et al. · Journal of Neuroscience · 1997 · 1.4K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

Mahmood Amiry‐Moghaddam, Takashi Otsuka, Patricia D. Hurn et al. · Proceedings of the National Academy of Sciences · 2003 · 535 citations

Medicine, Neurobiology, Neuroscience +13

Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal M�ller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains

Erlend A. Nagelhus, Yoshiyuki Horio, Atsushi Inanobe et al. · Glia · 1999 · 465 citations

Natural Sciences, Cell Biology, Neurobiology +17

Genetic Inactivation of an Inwardly Rectifying Potassium Channel (Kir4.1 Subunit) in Mice: Phenotypic Impact in Retina

Paulo Kofuji, Paul W. Ceelen, Kathleen R. Zahs et al. · Journal of Neuroscience · 2000 · 456 citations · Full text

Medicine, Cell Biology, Ophthalmology +17