Concepedia

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses

Tetsuo Takehara, Tomohide Tatsumi, Takahiro Suzuki, Edmund B. Rucker, Lothar Hennighausen, Masahisa Jinushi, Takuya Miyagi, Yoshiyuki Kanazawa, Norio Hayashi

Gastroenterology · 2004 · 220 citations · 28 references

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28

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Valerie A. Fadok, Donna L. Bratton, Anatole Konowal et al. · Journal of Clinical Investigation · 1998 · 3.1K citations · Full text

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Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

Catherine Postic, Masakazu Shiota, Kevin D. Niswender et al. · Journal of Biological Chemistry · 1999 · 1.3K citations · Full text

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Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

Noboru Motoyama, Fanping Wang, Kevin A. Roth et al. · Science · 1995 · 1.2K citations

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RNA interference targeting Fas protects mice from fulminant hepatitis

Erwei Song, Sang‐Kyung Lee, Jie Wang et al. · Nature Medicine · 2003 · 1.1K citations

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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Mai-Lan N. Huynh, Valerie A. Fadok, Peter M. Henson · Journal of Clinical Investigation · 2002 · 1.1K citations · Full text

, , +16