Different Profiles of Wheat Antigens Are Recognised by Patients Suffering from Coeliac Disease and IgE-Mediated Food Allergy

Abstract

This study thus demonstrates that wheat contains antigens/epitopes which are preferentially recognised by CD patients, whereas others elicit IgE-mediated food allergy. This finding suggests that the nature of a food antigen may influence the quality of the pathological immune response in the gut and has implications for the diagnosis and therapy of hypersensitivity to wheat.