PubMed · 1993 · 24 citations · 13 references
MedicineDermatologyPathologyDermatopathologyImmunogeneticsImmunopathologyImmunodeficiency DisordersImmunopathology Of SkinInfectious DermatosesKaposi SarcomaSexually Transmitted InfectionsSoft Tissue SarcomasCutaneous ImmunologyGermline PredispositionViral CultureVisceral Involvement
We report the first case of AIDS-associated Kaposi's Sarcoma in a 35 year old Indian female, a commercial sex worker, with lesions involving skin and mucous membranes. Diagnosis was confirmed on histopathology, electron microscopy, seropositivity, (ELISA and Western Blot) as well as Pepti-LAV test and viral culture. Antibodies to human immunodeficiency virus, both HIV-1 & 2, were present. HLA DR5,7 was positive on oligotyping. Genetic predisposition, therefore, may be suspected.
13