Effects of intrathecal morphine, clonidine and baclofen on allodynia after partial sciatic nerve injury in the rat

Abstract

The present data suggest that intrathecal morphine, and to some extent clonidine, but not baclofen, alleviated the abnormal pain-related behaviors in this new rat model of partial peripheral nerve injury. Differences in the pharmacological profile between the present model and other models of peripheral nerve injury are discussed.