Cruciate ligament laxity and femoral intercondylar notch narrowing in early‐stage knee osteoarthritis

Abstract

In DH guinea pigs, laxer ACLs, which are associated with increased collagen turnover, may cause joint instability and predispose these animals to the early onset of OA. Decreased intercondylar notch width in the DH animals indicates that bone remodeling at the ACL insertion site is a response to elevated ACL laxity.