Self‐Assembled Peptide Amphiphile Micelles Containing a Cytotoxic T‐Cell Epitope Promote a Protective Immune Response In Vivo

Abstract

A model cytotoxic T-cell epitope is linked to a synthetic lipid tail, forming a peptide amphiphile that self-assembles into cylindrical micelles. The micelles are capable of inducing a cytotoxic T-cell response in mice that slows the growth of tumors expressing the tumor antigen.