Concepedia

Continuous enzymatic synthesis of aspartame precursor at low pH using an extractive reaction

Yoshihiko Murakami, Akira Hirata

Journal of Fermentation and Bioengineering · 1997 · 24 citations · 21 references

DOI

Concepts

References

21

Protease‐Catalyzed Kinetically Controlled Peptide Synthesis

Volker Schellenberger, Hans‐Dieter Jakubke · Angewandte Chemie International Edition in English · 1991 · 198 citations

, , +15

Synthesis of an aspartame precursor by immobilized thermolysin in an organic solvent

Kiyotaka Oyama, Shigeaki Nishimura, Yuji Nonaka et al. · The Journal of Organic Chemistry · 1981 · 130 citations

, , +10

The thermolysin-catalyzed condensation reactions of n-substituted aspartic and glutamic acids with phenylalanine alkyl esters

Yoshikazu Isowa, Muneki Ohmori, Tetsuya Ichikawa et al. · Tetrahedron Letters · 1979 · 119 citations

, , +8

Continuous Synthesis of N-(Benzyloxycarbonyl)-L-Aspartyl-L-Phenylalanine Methyl Ester with Immobilized Thermolysin in an Organic Solvent

Kazuki Nakanishi, Tadashi Kamikubo, Ryuichi Matsuno · Nature Biotechnology · 1985 · 82 citations

, , +15

Kinetics and equilibrium of enzymatic synthesis of peptides in aqueous/organic biphasic systems

Kazuhiro Nakanishi, Yukitaka Kimura, Ryuichi Matsuno · European Journal of Biochemistry · 1986 · 70 citations · Full text

, , +17