Concepedia

High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir

Maria Jesús Pérez‐Elías, Santiago Moreno, Carolina Gutiérrez, Dolores López, Víctor Abraira, Ana Moreno, Fernando Dronda, José L. Casado, Antonio Antela, Miguel Ángel Palomero Rodríguez

AIDS · 2005 · 25 citations · 5 references

DOI

Abstract

Even in patients with suppressed viraemia, a two NRTI plus tenofovir regimen is associated with a high virological failure rate, but significant variations are found depending on the nucleosides included.

References

5

Triple-Nucleoside Regimens versus Efavirenz-Containing Regimens for the Initial Treatment of HIV-1 Infection

Roy M. Gulick, Heather J. Ribaudo, Cecilia M. Shikuma et al. · New England Journal of Medicine · 2004 · 526 citations · Full text

Substitution of Nevirapine, Efavirenz, or Abacavir for Protease Inhibitors in Patients with Human Immunodeficiency Virus Infection

Estebán Martínez, Juan A. Arnaiz, Daniel Podzamczer et al. · New England Journal of Medicine · 2003 · 293 citations · Full text

A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients

Remko van Leeuwen, Christine Katlama, Robert L. Murphy et al. · AIDS · 2003 · 171 citations

Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naive chronically HIV-1-infected individuals

Michael J. Louie, Christine Hogan, Arlene Hurley et al. · AIDS · 2003 · 84 citations

Change to abacavir-lamivudine-tenofovir combination treatment in patients with HIV-1 who had complete virological suppression

Martine Hoogewerf, R. M. Regez, WEM Schouten et al. · The Lancet · 2003 · 55 citations

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