Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models

Publication | Open Access

DOI Full Paper Access

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References

2015

Year

Stefanie Schrauwen, Jeroen Depreeuw, Lieve Coenegrachts, Els Hermans, Diether Lambrechts, Frédéric Amant

Gynecologic Oncology

OncologyMedicineInhibit GrowthGynecologyCancer GrowthDual BlockadeCorresponding Xenograft ModelsCancer BiologyCell BiologyCancer ResearchTumor BiologyEndocrine-related Cancer