Concepedia

Ion channel formation by Alzheimer's disease amyloid β-peptide (Aβ40) in unilamellar liposomes is determined by anionic phospholipids

Juan Marcos Alarcón, Julio A. Brito, Tamara Hermosilla, I. Atwater, David Mears, Eduardo Rojas

Peptides · 2005 · 66 citations · 54 references

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54

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

MP Mattson, Bin Cheng, David L. Davis et al. · Journal of Neuroscience · 1992 · 1.6K citations · Full text

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Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦

Angelo Demuro, Erene Mina, Rakez Kayed et al. · Journal of Biological Chemistry · 2005 · 1K citations · Full text

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Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum.

Nelson Arispe, E Rojas, Harvey B. Pollard · Proceedings of the National Academy of Sciences · 1993 · 928 citations

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Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases

Rakez Kayed, Yuri Sokolov, Brian Edmonds et al. · Journal of Biological Chemistry · 2004 · 904 citations · Full text

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Amyloid β protein forms ion channels: implications for Alzheimer's disease pathophysiology

Hai Lin, Rajinder Bhatia, Ratneshwar Lal · The FASEB Journal · 2001 · 642 citations

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