A Randomized Trial of Vitamin D₃Supplementation in Children: Dose-Response Effects on Vitamin D Metabolites and Calcium Absorption

Abstract

Large increases in serum 25(OH)D with vitamin D₃ supplementation did not increase calcium absorption in healthy children living at 2 different latitudes. Supplementation with 400 IU/d was sufficient to maintain wintertime 25(OH)D concentrations in healthy black, but not white, children.