Ultrasmall NaGdF₄ Nanodots for Efficient MR Angiography and Atherosclerotic Plaque Imaging

Abstract

Herein, ultrasmall NaGdF4 nanodots (~2 nm) with DTPA conjugation have been synthesized for efficient MR angiography. Impressively, the r1 value in MRI reaches up to 8.93 mM−1·s−1. The ultrasmall vessel lumen of a rabbit is lighted up remarkably. After 3 h, atherosclerotic plaques could be discriminated clearly. This is beneficial for the accurate early diagnosis of vascular pathema. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.