MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Rosalind C. Lee, Rhonda Feinbaum, Victor Ambros · Cell · 1993 · 12.7K citations · Full text

Prediction of Mammalian MicroRNA Targets

Benjamin P. Lewis, I‐hung Shih, Matthew W. Jones-Rhoades et al. · Cell · 2003 · 5.2K citations · Full text

Genetics, Gene Expression, Microrna Detection +7

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Brenda J. Reinhart, Frank J. Slack, Michael Basson et al. · Nature · 2000 · 4.9K citations

Developmental Timing, Developmental Biology, Genetics +6

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lee P. Lim, Nelson C. Lau, Philip W. Garrett-Engele et al. · Nature · 2005 · 4.8K citations

Target Mrnas, Systems Biology, Functional Genomics +13

Combinatorial microRNA target predictions

Azra Krek, Dominic Grün, Matthew N. Poy et al. · Nature Genetics · 2005 · 4.6K citations

Systems Biology, Functional Genomics, Genetics +6