Concepedia

Controlling 310-Helix and .ALPHA.-Helix of Short Peptides in the Solid State

Yosuke Demizu, Masakazu Tanaka, Masanobu Nagano, Masaaki Kurihara, Mitsunobu Doi, Tokumi Maruyama, Hiroshi Suemune

Chemical and Pharmaceutical Bulletin · 2007 · 44 citations · 11 references

DOIFull text

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Concepts

Abstract

L-Leu hexapeptide containing alpha-aminoisobutyric acid (Aib) forms a right-handed (P) 3(10)-helix, whereas that containing cyclic alpha,alpha-disubstituted amino acid Ac(5)c(dOM) assumes a right-handed (P) alpha-helix in the solid state.

References

11

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X‐ray crystallography of peptides: The contributions of the Italian laboratories

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Quantitative Correlation of Solvent Polarity with the α‐/3<sub>10</sub>‐Helix Equilibrium: A Heptapeptide Behaves as a Solvent‐Driven Molecular Spring

Paolo Pengo, Lucia Pasquato, Stefano Moro et al. · Angewandte Chemie International Edition · 2003 · 97 citations · Full text

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Chiral Centers in the Side Chains of α‐Amino Acids Control the Helical Screw Sense of Peptides

Masakazu Tanaka, Yosuke Demizu, Mitsunobu Doi et al. · Angewandte Chemie International Edition · 2004 · 62 citations

, , +17