Gemcitabine Reverses Cisplatin Resistance: Demonstration of Activity in Platinum- and Multidrug-Resistant Ovarian and Peritoneal Carcinoma

Action of 2',2'-difluorodeoxycytidine on DNA synthesis.

Peng Huang, Sherri Chubb, Larry W. Hertel et al. · PubMed · 1991 · 884 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Biochemistry +9

Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin.

Maurie Markman, Robert Rothman, Thomas B. Hakes et al. · Journal of Clinical Oncology · 1991 · 851 citations

Surgical Oncology, Overall Response Rates, Cisplatin Programs +12

Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.

Volker Heinemann, Larry W. Hertel, Gerald B. Grindey et al. · PubMed · 1988 · 509 citations

Hematological Malignancy, Medicinal Chemistry, Chemoprevention Strategy +15

Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy.

Meenakshi Dabholkar, Justine Vionnet, Jin‐Tai Yu et al. · Journal of Clinical Investigation · 1994 · 446 citations · Full text

Ercc1 Mrna, Oncogenic Agent, Medicine +15

Defining response of ovarian carcinoma to initial chemotherapy according to serum CA 125.

G.J.S. Rustin, Ann E. Nelstrop, Patrick McClean et al. · Journal of Clinical Oncology · 1996 · 377 citations