Synthesis of non-natural glycosylamino acids containing tumor-associated carbohydrate antigens

T and Tn, General Carcinoma Autoantigens

Georg F. Springer · Science · 1984 · 1K citations

Medicine, Immunology, Tumor Immunity +14

Glycals in Organic Synthesis: The Evolution of Comprehensive Strategies for the Assembly of Oligosaccharides and Glycoconjugates of Biological Consequence

Samuel J. Danishefsky, Mark T. Bilodeau · Angewandte Chemie International Edition in English · 1996 · 685 citations

Solid Phase, Bioorganic Chemistry, Complex Dienes +20

From the Laboratory to the Clinic: A Retrospective on Fully Synthetic Carbohydrate-Based Anticancer Vaccines

Samuel J. Danishefsky, Jennifer R. Allen · Angewandte Chemie International Edition · 2000 · 508 citations

Immunology, Glycobiology, Selective Carbohydrate Motifs +21

Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope.

Thomas Kjeldsen, H Clausen, S Hirohashi et al. · PubMed · 1988 · 427 citations

Tumor Biology, Immunocytochemical Technique, Galnac Alpha 1 +13

Synthetic and Immunological Studies on Clustered Modes of Mucin-Related Tn and TF O-Linked Antigens:  The Preparation of a Glycopeptide-Based Vaccine for Clinical Trials against Prostate Cancer

Scott D. Kuduk, Jacob B. Schwarz, Xiaotao Chen et al. · Journal of the American Chemical Society · 1998 · 204 citations

Immunology, Immunoediting, Immunodominance +22