Concepedia

Differences in Gene Expression between First and Third Trimester Human Placenta: A Microarray Study

Vasilis Sitras, Christopher G. Fenton, Ruth H. Paulssen, Åse Vårtun, Ganesh Acharya

PLoS ONE · 2012 · 94 citations · 28 references

DOIFull text

Open access

Abstract

Differences in global gene expression profile between first and third trimester human placenta reflect temporal changes in placental structure and function. Epigenetic rearrangements in the human placenta seem to occur across gestation, indicating the importance of environmental influence in the developing feto-placental unit.

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